Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans.

The effects of probenecid on the pharmacokinetics and renal clearance of acyclovir were studied in humans. Acyclovir (5 mg/kg) was given as a 1-h infusion to three volunteers with normal renal function both before and after oral administration of probenecid (1 g). The kinetics were well described by...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Laskin, O L, de Miranda, P, King, D H, Page, D A, Longstreth, J A, Rocco, L, Lietman, P S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182015/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7103460/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.5.804
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