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Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans.

The effects of probenecid on the pharmacokinetics and renal clearance of acyclovir were studied in humans. Acyclovir (5 mg/kg) was given as a 1-h infusion to three volunteers with normal renal function both before and after oral administration of probenecid (1 g). The kinetics were well described by...

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Main Authors: Laskin, O L, de Miranda, P, King, D H, Page, D A, Longstreth, J A, Rocco, L, Lietman, P S
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC182015/
https://ncbi.nlm.nih.gov/pubmed/7103460
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