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Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers.

Because of the incomplete absorption of acyclovir (ACV) when given orally in humans, efforts have been made to develop a prodrug of ACV that would be better absorbed from the gastrointestinal tract and then converted in vivo to ACV. One such compound, desciclovir (DCV), is converted to acyclovir in...

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Autors principals: Petty, B G, Whitley, R J, Liao, S, Krasny, H C, Rocco, L E, Davis, L G, Lietman, P S
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC174934/
https://ncbi.nlm.nih.gov/pubmed/3674844
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