Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers.

Because of the incomplete absorption of acyclovir (ACV) when given orally in humans, efforts have been made to develop a prodrug of ACV that would be better absorbed from the gastrointestinal tract and then converted in vivo to ACV. One such compound, desciclovir (DCV), is converted to acyclovir in...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Petty, B G, Whitley, R J, Liao, S, Krasny, H C, Rocco, L E, Davis, L G, Lietman, P S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174934/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3674844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.9.1317
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