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Activated calcineurin ameliorates contraction-induced injury to skeletal muscles of mdx dystrophic mice
Utrophin expression is regulated by calcineurin and up-regulating utrophin can decrease the susceptibility of dystrophic skeletal muscle to contraction-induced injury. We overexpressed the constitutively active calcineurin-A α in skeletal muscle of mdx dystrophic mice (mdx CnA*) and examined the tib...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1819459/ https://ncbi.nlm.nih.gov/pubmed/16793906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.108472 |
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