FBXW7/hCDC4 controls glioma cell proliferation in vitro and is a prognostic marker for survival in glioblastoma patients

BACKGROUND: In the quest for novel molecular mediators of glioma progression, we studied the regulation of FBXW7 (hCDC4/hAGO/SEL10), its association with survival of patients with glioblastoma and its potential role as a tumor suppressor gene in glioma cells. The F-box protein Fbxw7 is a component o...

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Autori principali: Hagedorn, Martin, Delugin, Maylis, Abraldes, Isabelle, Allain, Nathalie, Belaud-Rotureau, Marc-Antoine, Turmo, Michelle, Prigent, Claude, Loiseau, Hugues, Bikfalvi, Andréas, Javerzat, Sophie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819378/
https://ncbi.nlm.nih.gov/pubmed/17326833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-2-9
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