Activity of trifluorothymidine against cytomegalovirus.

Trifluorothymidine (TFT) was tested for antiviral activity against mouse cytomegalovirus (MCMV) and human cytomegalovirus (HCMV) in one-step replication assays. The TFT concentration required to reduce virus yield by 50% (ID50) was 0.22 microM for MCMV and 0.012 microM for HCMV. The antiviral activi...

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Bibliographic Details
Main Authors: Wingard, J R, Stuart, R K, Saral, R, Burns, W H
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC181689/
https://ncbi.nlm.nih.gov/pubmed/6272627
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