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Properties of Streptomyces fradiae Mutants Blocked in Biosynthesis of the Macrolide Antibiotic Tylosin

We isolated numerous mutants of Streptomyces fradiae blocked in tylosin biosynthesis after N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis. These mutants were classified into nine groups, based upon the tylosin-like compounds produced and upon cofermentation analyses. More than 80% of the mutants i...

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Detalhes bibliográficos
Main Authors: Baltz, Richard H., Seno, Eugene T.
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC181666/
https://ncbi.nlm.nih.gov/pubmed/7283418
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