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The catalytic subunit of DNA–protein kinase (DNA-PKcs) is not required for Ig class-switch recombination
The joining of DNA ends during Ig class-switch recombination (CSR) is thought to involve the same nonhomologous end-joining pathway as used in V(D)J recombination. However, we reported earlier that CSR can readily occur in Ig transgenic SCID mice lacking DNA-dependent protein kinase (DNA-PK) activit...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815269/ https://ncbi.nlm.nih.gov/pubmed/17296939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611359104 |
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