Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination

HIV-1 tat targets a variety of host cell proteins to facilitate viral transcription and disrupts host cellular immunity by inducing lymphocyte apoptosis, but whether it influences humoral immunity remains unclear. Previously, our group demonstrated that tat depresses expression of DNA-PKcs, a critic...

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Detalhes bibliográficos
Main Authors: Zhang, Shi-Meng, Zhang, He, Yang, Tian-Yi, Ying, Tian-Yi, Yang, Pei-Xiang, Liu, Xiao-Dan, Tang, Sheng-Jian, Zhou, Ping-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202030/
https://ncbi.nlm.nih.gov/pubmed/25332688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10366
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