The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

The homeobox transcription factor CDX2 plays an important role in embryonic development and regulates the proliferation and differentiation of intestinal epithelial cells in the adult. We have found that CDX2 is expressed in leukemic cells of 90% of patients with acute myeloid leukemia (AML) but not...

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Main Authors: Scholl, Claudia, Bansal, Dimple, Döhner, Konstanze, Eiwen, Karina, Huntly, Brian J.P., Lee, Benjamin H., Rücker, Frank G., Schlenk, Richard F., Bullinger, Lars, Döhner, Hartmut, Gilliland, D. Gary, Fröhling, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810574/
https://ncbi.nlm.nih.gov/pubmed/17347684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30182
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