Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model

HOX genes have emerged as critical effectors of leukemogenesis, but the mechanisms that regulate their expression in leukemia are not well understood. Recent data suggest that the caudal homeobox transcription factors CDX1, CDX2, and CDX4, developmental regulators of HOX gene expression, may contrib...

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書誌詳細
主要な著者: Bansal, Dimple, Scholl, Claudia, Fröhling, Stefan, McDowell, Elizabeth, Lee, Benjamin H., Döhner, Konstanze, Ernst, Patricia, Davidson, Alan J., Daley, George Q., Zon, Leonard I., Gilliland, D. Gary, Huntly, Brian J. P.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636555/
https://ncbi.nlm.nih.gov/pubmed/17068127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604579103
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