The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed in patients with acute erythroid leukemia, and that aberrant expression of Cdx4 induced homogenously a transplan...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Thoene, Silvia, Mandal, Tamoghna, Vegi, Naidu M., Quintanilla-Martinez, Leticia, Rösler, Reinhild, Wiese, Sebastian, Metzeler, Klaus H., Herold, Tobias, Haferlach, Torsten, Döhner, Konstanze, Döhner, Hartmut, Schwarzmüller, Luisa, Klingmüller, Ursula, Buske, Christian, Rawat, Vijay P. S., Feuring-Buske, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880902/
https://ncbi.nlm.nih.gov/pubmed/31770439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000761
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