The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed in patients with acute erythroid leukemia, and that aberrant expression of Cdx4 induced homogenously a transplan...

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Bibliografiska uppgifter
I publikationen:Blood Adv
Huvudupphovsmän: Thoene, Silvia, Mandal, Tamoghna, Vegi, Naidu M., Quintanilla-Martinez, Leticia, Rösler, Reinhild, Wiese, Sebastian, Metzeler, Klaus H., Herold, Tobias, Haferlach, Torsten, Döhner, Konstanze, Döhner, Hartmut, Schwarzmüller, Luisa, Klingmüller, Ursula, Buske, Christian, Rawat, Vijay P. S., Feuring-Buske, Michaela
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2019
Ämnen:
Myeloid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880902/
https://ncbi.nlm.nih.gov/pubmed/31770439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000761
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