The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

The homeobox transcription factor CDX2 plays an important role in embryonic development and regulates the proliferation and differentiation of intestinal epithelial cells in the adult. We have found that CDX2 is expressed in leukemic cells of 90% of patients with acute myeloid leukemia (AML) but not...

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Bibliografiske detaljer
Main Authors: Scholl, Claudia, Bansal, Dimple, Döhner, Konstanze, Eiwen, Karina, Huntly, Brian J.P., Lee, Benjamin H., Rücker, Frank G., Schlenk, Richard F., Bullinger, Lars, Döhner, Hartmut, Gilliland, D. Gary, Fröhling, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810574/
https://ncbi.nlm.nih.gov/pubmed/17347684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30182
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