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Deficiency of Src homology 2 domain–containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth
Platelets are critical for normal hemostasis. Their deregulation can lead to bleeding or to arterial thrombosis, a primary cause of heart attack and ischemic stroke. Src homology 2 domain–containing inositol 5-phosphatase 1 (SHIP1) is a 5-phosphatase capable of dephosphorylating the phosphatidylinos...
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Main Authors: | , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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American Society for Clinical Investigation
2007
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810573/ https://ncbi.nlm.nih.gov/pubmed/17347685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29967 |
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