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pp60c-src associates with the SH2-containing inositol-5-phosphatase SHIP1 and is involved in its tyrosine phosphorylation downstream of alphaIIbbeta3 integrin in human platelets.

SH2-containing inositol-5-phosphatase 1 (SHIP1) was originally identified as a 145 kDa protein that became tyrosine-phosphorylated in response to multiple cytokines. It is now well established that SHIP1 is specifically expressed in haemopoietic cells and is important as a negative regulator of sign...

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Bibliografiske detaljer
Main Authors: Giuriato, S, Bodin, S, Erneux, C, Woscholski, R, Plantavid, M, Chap, H, Payrastre, B
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221042/
https://ncbi.nlm.nih.gov/pubmed/10794720
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