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Advantages to the Use of Rodent Hepadnavirus Core Proteins as Vaccine Platforms
The hepatitis B core antigen (HBcAg) has been proposed as a useful particulate carrier platform for poorly immunogenic peptidic and carbohydrate B cell epitopes. However, biochemical and immunologic impediments have plagued this technology. Specifically, the “assembly” problem characterized by the l...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1810237/ https://ncbi.nlm.nih.gov/pubmed/17178179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.11.013 |
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