Advantages to the Use of Rodent Hepadnavirus Core Proteins as Vaccine Platforms

The hepatitis B core antigen (HBcAg) has been proposed as a useful particulate carrier platform for poorly immunogenic peptidic and carbohydrate B cell epitopes. However, biochemical and immunologic impediments have plagued this technology. Specifically, the “assembly” problem characterized by the l...

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Hlavní autoři: Billaud, Jean–Noel, Peterson, Darrell, Lee, Byung O., Maruyama, Toshiyuki, Chen, Antony, Sallberg, Matti, Garduño, Fermin, Goldstein, Phillip, Hughes, Janice, Jones, Joyce, Milich, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810237/
https://ncbi.nlm.nih.gov/pubmed/17178179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2006.11.013
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