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Use of hepadnavirus core proteins as vaccine platforms

The first virus-like particle to be tested for use as a vaccine carrier was based on the hepatitis B virus nucleocapsid protein. This viral subunit, while not infectious on its own, is a 36-nm particle that is highly immunogenic during a natural infection. The self-assembly and high degree of immuno...

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Autors principals: Whitacre, David C, Lee, Byung O, Milich, David R
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836209/
https://ncbi.nlm.nih.gov/pubmed/19863249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erv.09.121
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