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A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen
A unique characteristic of the hepatitis B virus is the production of a secreted form (precore or HBeAg) of the structural nucleocapsid (core or HBcAg). By using T cell receptor (TCR) transgenic (Tg) and TCR × HBc/HBeAg double- and triple-Tg pairs, we demonstrate that HBeAg elicits T cell tolerance,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522042/ https://ncbi.nlm.nih.gov/pubmed/15469922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406282101 |
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