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Pneumolysin-mediated activation of NFκB in human neutrophils is antagonized by docosahexaenoic acid

This study was designed to investigate the relationship between influx of extracellular Ca(2+), activation of NFκB and synthesis of interleukin-8 (IL-8) following exposure of human neutrophils to subcytolytic concentrations (8·37 and 41·75 ng/ml) of the pneumococcal toxin, pneumolysin, as well as th...

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Autori principali: Fickl, H, Cockeran, R, Steel, H C, Feldman, C, Cowan, G, Mitchell, T J, Anderson, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809376/
https://ncbi.nlm.nih.gov/pubmed/15807851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02757.x
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