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Pneumolysin activates neutrophil extracellular trap formation

The primary objective of the current study was to investigate the potential of the pneumococcal toxin, pneumolysin (Ply), to activate neutrophil extracellular trap (NET) formation in vitro. Isolated human blood neutrophils were exposed to recombinant Ply (5‐20 ng ml(−1)) for 30–90 min at 37°C and NE...

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Détails bibliographiques
Publié dans:Clin Exp Immunol
Auteurs principaux: G. Nel, J., Theron, A. J., Durandt, C., Tintinger, G. R., Pool, R., Mitchell, T. J., Feldman, C., Anderson, R.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872380/
https://ncbi.nlm.nih.gov/pubmed/26749379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12766
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