Itraconazole-mediated inhibition of calcium entry into platelet-activating factor-stimulated human neutrophils is due to interference with production of leukotriene B(4)

The primary objective of this study was to probe the involvement of leukotriene B(4) (LTB(4)) in itraconazole (0·1–5 µM)-mediated inhibition of Ca(2+) uptake by chemoattractant-activated human neutrophils. Following exposure of the cells to platelet-activating factor (PAF, 200 nM), LTB(4) was measur...

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Detaylı Bibliyografya
Asıl Yazarlar: Steel, H C, Tintinger, G R, Theron, A J, Anderson, R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2007
Konular:
Basic Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219290/
https://ncbi.nlm.nih.gov/pubmed/17683509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03470.x
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