Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C

BACKGROUND: The role of protein kinase C (PKC) in regulating the activity of phospholipase C (PLC) in neutrophils activated with the chemoattractant, platelet-activating factor (PAF, 20 and 200 nM), was probed in the current study using the selective PKC inhibitors, GF10903X (0.5 - 1 μM) and stauros...

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Detalhes bibliográficos
Main Authors: Tintinger, Gregory R, Theron, Annette J, Steel, Helen C, Cockeran, Riana, Pretorius, Lynette, Anderson, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777896/
https://ncbi.nlm.nih.gov/pubmed/19874629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-6-29
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