Pneumolysin Potentiates Production of Prostaglandin E(2) and Leukotriene B(4) by Human Neutrophils

Exposure to pneumolysin (8.37 and 41.75 ng/ml) caused a calcium-dependent increase in the generation of prostaglandin E(2) and leukotriene B(4) by both resting and chemoattractant-activated human neutrophils in vitro. These interactions of pneumolysin with neutrophils may result in dysregulation of...

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Main Authors: Cockeran, Riana, Steel, Helen C., Mitchell, Timothy J., Feldman, Charles, Anderson, Ronald
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC98318/
https://ncbi.nlm.nih.gov/pubmed/11292782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3494-3496.2001
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