Decreased Virulence of a Pneumolysin-Deficient Strain of Streptococcus pneumoniae in Murine Meningitis

Pneumolysin, neuraminidases A and B, and hyaluronidase are virulence factors of Streptococcus pneumoniae that appear to be involved in the pathogenesis of meningitis. In a murine model of meningitis after intracerebral infection using mutants of S. pneumoniae D39, only mice infected with a pneumolys...

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Detalhes bibliográficos
Main Authors: Wellmer, Andreas, Zysk, Gregor, Gerber, Joachim, Kunst, Tammo, von Mering, Matthias, Bunkowski, Stefanie, Eiffert, Helmut, Nau, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130334/
https://ncbi.nlm.nih.gov/pubmed/12379738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.11.6504-6508.2002
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