Rad53 Phosphorylation Site Clusters Are Important for Rad53 Regulation and Signaling

Budding yeast Rad53 is an essential protein kinase that is phosphorylated and activated in a MEC1- and TEL1-dependent manner in response to DNA damage. We studied the role of Rad53 phosphorylation through mutation of consensus phosphorylation sites for upstream kinases Mec1 and Tel1. Alanine substit...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lee, Soo-Jung, Schwartz, Marc F., Duong, Jimmy K., Stern, David F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6300-6314.2003
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