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Rad53 Phosphorylation Site Clusters Are Important for Rad53 Regulation and Signaling

Budding yeast Rad53 is an essential protein kinase that is phosphorylated and activated in a MEC1- and TEL1-dependent manner in response to DNA damage. We studied the role of Rad53 phosphorylation through mutation of consensus phosphorylation sites for upstream kinases Mec1 and Tel1. Alanine substit...

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Bibliografische gegevens
Hoofdauteurs: Lee, Soo-Jung, Schwartz, Marc F., Duong, Jimmy K., Stern, David F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC180918/
https://ncbi.nlm.nih.gov/pubmed/12917350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6300-6314.2003
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