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Rad53 Phosphorylation Site Clusters Are Important for Rad53 Regulation and Signaling
Budding yeast Rad53 is an essential protein kinase that is phosphorylated and activated in a MEC1- and TEL1-dependent manner in response to DNA damage. We studied the role of Rad53 phosphorylation through mutation of consensus phosphorylation sites for upstream kinases Mec1 and Tel1. Alanine substit...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC180918/ https://ncbi.nlm.nih.gov/pubmed/12917350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6300-6314.2003 |
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