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Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae
Budding yeast possesses a checkpoint-dependent mechanism of delaying G(1) progression in response to UV and ionizing radiation DNA damage. We have shown that after a pulse of DNA damage in G(1) with the alkylating agent MMS, there is also a MEC1-, RAD53-, and RAD9-dependent delay in G(1). This delay...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316703/ https://ncbi.nlm.nih.gov/pubmed/9367985 |
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