Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae
Budding yeast possesses a checkpoint-dependent mechanism of delaying G(1) progression in response to UV and ionizing radiation DNA damage. We have shown that after a pulse of DNA damage in G(1) with the alkylating agent MMS, there is also a MEC1-, RAD53-, and RAD9-dependent delay in G(1). This delay...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9367985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.22.3032 |
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