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Rad53-dependent phosphorylation of Swi6 and down-regulation of CLN1 and CLN2 transcription occur in response to DNA damage in Saccharomyces cerevisiae

Budding yeast possesses a checkpoint-dependent mechanism of delaying G(1) progression in response to UV and ionizing radiation DNA damage. We have shown that after a pulse of DNA damage in G(1) with the alkylating agent MMS, there is also a MEC1-, RAD53-, and RAD9-dependent delay in G(1). This delay...

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Bibliografske podrobnosti
izdano v:Genes Dev
Principais autores: Sidorova, Julia M., Breeden, Linda L.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1997
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9367985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.22.3032
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