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Formation of multinucleated giant cells and microglial degeneration in rats expressing a mutant Cu/Zn superoxide dismutase gene

BACKGROUND: Microglial neuroinflammation is thought to play a role in the pathogenesis of amyotrophic lateral sclerosis (ALS). The purpose of this study was to provide a histopathological evaluation of the microglial neuroinflammatory response in a rodent model of ALS, the SOD1(G93A )transgenic rat....

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Detalhes bibliográficos
Main Authors: Fendrick, Sarah E, Xue, Qing-Shan, Streit, Wolfgang J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808448/
https://ncbi.nlm.nih.gov/pubmed/17328801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-9
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