Rapid DNA mapping by fluorescent single molecule detection

DNA mapping is an important analytical tool in genomic sequencing, medical diagnostics and pathogen identification. Here we report an optical DNA mapping strategy based on direct imaging of individual DNA molecules and localization of multiple sequence motifs on the molecules. Individual genomic DNA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiao, Ming, Phong, Angie, Ha, Connie, Chan, Ting-Fung, Cai, Dongmei, Leung, Lucinda, Wan, Eunice, Kistler, Amy L., DeRisi, Joseph L., Selvin, Paul R., Kwok, Pui-Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807959/
https://ncbi.nlm.nih.gov/pubmed/17175538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1044
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