Rapid DNA mapping by fluorescent single molecule detection

DNA mapping is an important analytical tool in genomic sequencing, medical diagnostics and pathogen identification. Here we report an optical DNA mapping strategy based on direct imaging of individual DNA molecules and localization of multiple sequence motifs on the molecules. Individual genomic DNA...

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Detalhes bibliográficos
Main Authors: Xiao, Ming, Phong, Angie, Ha, Connie, Chan, Ting-Fung, Cai, Dongmei, Leung, Lucinda, Wan, Eunice, Kistler, Amy L., DeRisi, Joseph L., Selvin, Paul R., Kwok, Pui-Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807959/
https://ncbi.nlm.nih.gov/pubmed/17175538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1044
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