Rapid DNA mapping by fluorescent single molecule detection

DNA mapping is an important analytical tool in genomic sequencing, medical diagnostics and pathogen identification. Here we report an optical DNA mapping strategy based on direct imaging of individual DNA molecules and localization of multiple sequence motifs on the molecules. Individual genomic DNA...

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Bibliografiska uppgifter
Huvudupphovsmän: Xiao, Ming, Phong, Angie, Ha, Connie, Chan, Ting-Fung, Cai, Dongmei, Leung, Lucinda, Wan, Eunice, Kistler, Amy L., DeRisi, Joseph L., Selvin, Paul R., Kwok, Pui-Yan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2007
Ämnen:
Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807959/
https://ncbi.nlm.nih.gov/pubmed/17175538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1044
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