A simple DNA stretching method for fluorescence imaging of single DNA molecules

Stretching or aligning DNA molecules onto a surface by means of molecular combing techniques is one of the critical steps in single DNA molecule analysis. However, many of the current studies have focused on λ-DNA, or other large DNA molecules. There are very few studies on stretching methodologies...

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Bibliographic Details
Main Authors: Chan, Ting-Fung, Ha, Connie, Phong, Angie, Cai, Dongmei, Wan, Eunice, Leung, Lucinda, Kwok, Pui-Yan, Xiao, Ming
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635263/
https://ncbi.nlm.nih.gov/pubmed/16971459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl593
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