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The accessory subunit B of DNA polymerase γ is required for mitochondrial replisome function
The mitochondrial replication machinery in human cells includes the DNA polymerase γ holoenzyme and the TWINKLE helicase. Together, these two factors form a processive replication machinery, a replisome, which can use duplex DNA as template to synthesize long stretches of single-stranded DNA. We her...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1807957/ https://ncbi.nlm.nih.gov/pubmed/17251196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1116 |
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