Rapid conditional knock-down–knock-in system for mammalian cells

RNA interference (RNAi) is a powerful tool to analyze gene function in mammalian cells. However, the interpretation of RNAi knock-down phenotypes can be hampered by off-target effects or compound phenotypes, as many proteins combine multiple functions within one molecule and coordinate the assembly...

Full description

Saved in:
Bibliographic Details
Main Authors: Hölzel, Michael, Rohrmoser, Michaela, Orban, Mathias, Hömig, Cornelia, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, Heissmeyer, Vigo, Bornkamm, Georg, Eick, Dirk
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1807947/
https://ncbi.nlm.nih.gov/pubmed/17169998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1055
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items