Mammalian WDR12 is a novel member of the Pes1–Bop1 complex and is required for ribosome biogenesis and cell proliferation

Target genes of the protooncogene c-myc are implicated in cell cycle and growth control, yet the linkage of both is still unexplored. Here, we show that the products of the nucleolar target genes Pes1 and Bop1 form a stable complex with a novel member, WDR12 (PeBoW complex). Endogenous WDR12, a WD40...

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Hauptverfasser: Hölzel, Michael, Rohrmoser, Michaela, Schlee, Martin, Grimm, Thomas, Harasim, Thomas, Malamoussi, Anastassia, Gruber-Eber, Anita, Kremmer, Elisabeth, Hiddemann, Wolfgang, Bornkamm, Georg W., Eick, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171466/
https://ncbi.nlm.nih.gov/pubmed/16043514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200501141
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