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Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels
Drugs for cancer therapy belong to different categories of chemical substances. The cellular targets for the therapeutic efficacy are often not unambiguously identified. Here, we describe the process of ribosome biogenesis as a target of a large variety of chemotherapeutic drugs. We determined the i...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852979/ https://ncbi.nlm.nih.gov/pubmed/20159984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074211 |
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