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Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels
Drugs for cancer therapy belong to different categories of chemical substances. The cellular targets for the therapeutic efficacy are often not unambiguously identified. Here, we describe the process of ribosome biogenesis as a target of a large variety of chemotherapeutic drugs. We determined the i...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852979/ https://ncbi.nlm.nih.gov/pubmed/20159984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074211 |
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