Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.

Five herpes simplex virus mutants known or presumed to contain mutations in their DNA polymerase genes conferring resistance to acyclovir and arabinosyladenine also proved to exhibit some degree of resistance to (R)-9-(3,4-dihydroxybutyl)guanine (buciclovir). For one mutant, a buciclovir resistance...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Chiou, H C, Kerns, K M, Coen, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3022642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.502
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