Mode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovir.

9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine (3HM-HBG), (RS)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine ([+/-]2HM-HBG), and cis-9-(4-hydroxy-2-butenyl)guanine (2EN-HBG), new acyclic guanosine analogs structurally related to buciclovir (BCV [(R)-9-(3,4-dihydroxybutyl)guanine]), were evaluated in para...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Larsson, A, Stenberg, K, Ericson, A C, Haglund, U, Yisak, W A, Johansson, N G, Oberg, B, Datema, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3024562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.4.598
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