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Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.

Five herpes simplex virus mutants known or presumed to contain mutations in their DNA polymerase genes conferring resistance to acyclovir and arabinosyladenine also proved to exhibit some degree of resistance to (R)-9-(3,4-dihydroxybutyl)guanine (buciclovir). For one mutant, a buciclovir resistance...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chiou, H C, Kerns, K M, Coen, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC180588/
https://ncbi.nlm.nih.gov/pubmed/3022642
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