Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.

Five herpes simplex virus mutants known or presumed to contain mutations in their DNA polymerase genes conferring resistance to acyclovir and arabinosyladenine also proved to exhibit some degree of resistance to (R)-9-(3,4-dihydroxybutyl)guanine (buciclovir). For one mutant, a buciclovir resistance...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Chiou, H C, Kerns, K M, Coen, D M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1986
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3022642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.502
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