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Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine.

Five herpes simplex virus mutants known or presumed to contain mutations in their DNA polymerase genes conferring resistance to acyclovir and arabinosyladenine also proved to exhibit some degree of resistance to (R)-9-(3,4-dihydroxybutyl)guanine (buciclovir). For one mutant, a buciclovir resistance...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Chiou, H C, Kerns, K M, Coen, D M
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3022642/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.30.3.502
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