Charge and lipophilicity govern the pharmacokinetics of glycopeptide antibiotics.
The pharmacokinetics and urinary excretion of nine glycopeptide antibiotics with diverse pIs (3.8 to 8.5) and lipophilicities were studied. The disposition of the aridicin antibiotics and their hydrolysis products were examined in male CD-1 mice after subcutaneous and intravenous administration and...
محفوظ في:
| الحاوية / القاعدة: | Antimicrob Agents Chemother |
|---|---|
| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1986
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2940973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.3.440 |
| الوسوم: |
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