Charge and lipophilicity govern the pharmacokinetics of glycopeptide antibiotics.

The pharmacokinetics and urinary excretion of nine glycopeptide antibiotics with diverse pIs (3.8 to 8.5) and lipophilicities were studied. The disposition of the aridicin antibiotics and their hydrolysis products were examined in male CD-1 mice after subcutaneous and intravenous administration and...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Pitkin, D H, Mico, B A, Sitrin, R D, Nisbet, L J
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1986
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2940973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.3.440
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