Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis.

The pharmacokinetics and cerebrospinal fluid (CSF) penetration of cefotaxime (Ctx) and desacetylcefotaxime (dCtx) were evaluated in 13 infants and children with meningitis after dose 6 of Ctx in a multiple-dose intermittent intravenous infusion regimen (50 mg/kg every 6 h). Model-dependent and nonco...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Trang, J M, Jacobs, R F, Kearns, G L, Brown, A L, Wells, T G, Underwood, F L, Kluza, R B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1985
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4083862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.6.791
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