Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis.

The pharmacokinetics and cerebrospinal fluid (CSF) penetration of cefotaxime (Ctx) and desacetylcefotaxime (dCtx) were evaluated in 13 infants and children with meningitis after dose 6 of Ctx in a multiple-dose intermittent intravenous infusion regimen (50 mg/kg every 6 h). Model-dependent and nonco...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Trang, J M, Jacobs, R F, Kearns, G L, Brown, A L, Wells, T G, Underwood, F L, Kluza, R B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180330/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4083862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.6.791
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