Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis.

The pharmacokinetics and cerebrospinal fluid (CSF) penetration of cefotaxime (Ctx) and desacetylcefotaxime (dCtx) were evaluated in 13 infants and children with meningitis after dose 6 of Ctx in a multiple-dose intermittent intravenous infusion regimen (50 mg/kg every 6 h). Model-dependent and nonco...

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Autors principals: Trang, J M, Jacobs, R F, Kearns, G L, Brown, A L, Wells, T G, Underwood, F L, Kluza, R B
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC180330/
https://ncbi.nlm.nih.gov/pubmed/4083862
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