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Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis.

The pharmacokinetics and cerebrospinal fluid (CSF) penetration of cefotaxime (Ctx) and desacetylcefotaxime (dCtx) were evaluated in 13 infants and children with meningitis after dose 6 of Ctx in a multiple-dose intermittent intravenous infusion regimen (50 mg/kg every 6 h). Model-dependent and nonco...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Trang, J M, Jacobs, R F, Kearns, G L, Brown, A L, Wells, T G, Underwood, F L, Kluza, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1985
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4083862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.28.6.791
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